PMID: 33508266 P-49 First report of hereditary angioedema due to C1-inhibitor deficiency in Bosnia and Herzegovina: Novel mutation and evidence of genotypephenotype association Mensuda Hasanhodzic 1 , Azra Lukavackic 1 , Aneta Vareskic 1 , Matija Rijavec 2 1 University Clinical Centre Tuzla, Centre for Rare Diseases and Medical Gitenetics, Tuzla, Bosnia and Herzegovina
A case report and survey
Insulin primarily enters the brain via selective, saturable transport across the blood-brain barrier (BBB) 373,374,375 Peripherally produced insulin can also be actively transported into the brain via an endocytic-exocytic mechanism
In rodent models, activation of the GLP-1 neurons also results in activation of stress responses, including anxiety-like behavior (Maniscalco and Rinaman, 2018)
Not enough is known about the use of L-Carnitine during pregnancy and breast-feeding
The clinical application of tirzepatide as a treatment for T2D has the potential to provide new insights into the disease and help unravel the role of GIP in its development