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Summary: Retatrutide is an unlicensed investigational drug in the UK, administered as a once-weekly subcutaneous injection only within approved clinical trials under medical supervision

Bacteriostatic Water for Injection, USP prescribing information

Like most things, being specific is important, but being specific is also difficult. Peptides can have major, poorly-understood effects

NCT03600480), in which 96 participants with a BMI of 27.039.9 kg/m were randomised 3:1 to once-weekly subcutaneous cagrilintide (0.16, 0.30, 0.60, 1.2, 2.4 or 4.5 mg) or matched placebo, each in combination with once-weekly semaglutide 2.4 mg , across six sequential overlapping cohorts

& Nattel, S