An emerging mechanism, cartilage regeneration In the last decade, studies have appeared suggesting that AOD-9604 may also have an effect on cartilage regeneration (chondrocytes)
Deficiency may result from poor absorption due to low intrinsic factors, chronic gastritis, autoimmune conditions, stomach surgery, or certain medications that reduce stomach acid
Key takeaways You cant directly equate B12 pills to B12 shots because your body absorbs them differently
If youre trying the liquid method, you put drops under your tongue instead of ingesting them like you would an oral supplement
Special populations, such as post-bariatric surgery patients and those on metformin, may require tailored dosing regimens to ensure adequate vitamin B12 levels

* --- Some additional studies of low B12 and poor cognition Metabolic vitamin B12 deficiency: a missed opportunity to prevent dementia and stroke- 2015 Vitamin B12 status, cognitive decline and dementia: a systematic review of prospective cohort studies - 2012 FREE PDF Higher vitamin B12 level at Parkinson's disease diagnosis is associated with lower risk of future dementia - April 2020, Low Vitamin B12 Levels: An Underestimated Cause Of Minimal Cognitive Impairment And Dementia - Feb 2020 FREE PDF, Prevalence of vitamin B12 deficiency in elderly population with dementia - Feb 2020 FREE PDF Possible role of vitamin B12 in cognitive decline seen in dementia and Alzheimers disease - PhD Thesis Metformin (oral glucose-lowering drug) causes B12 deficiency - July 2021 * Long-term metformin therapy and vitamin B12 deficiency: An association to bear in mind * DOI: 10.4239/wjd.v12.i7.916 FREE PDF Unraveling The Complexity Of Vitamin B12 Diseases - Jan 2022 * ScienceBlog Baylor University * Tackling the complexity of two inherited vitamin B12 diseases Vitamin B-12 and the Gastrointestinal Microbiome - March 2022 * A Systematic Review * behind paywall ABSTRACT Vitamin B-12 deficiency is a major public health problem affecting individuals across the lifespan, with known hematological, neurological, and obstetric consequences
