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In a murine model, autophagy was shown to play a role in CSC regulation through the EGFR/STAT3 and TGF-/Smad signaling pathways in two distinct populations of breast cancer stem-like cells [114]
AA: Writing review & editing, Validation, Data curation, Supervision, Conceptualization
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After a final wash step, a tetramethylbenzidine (TMB) peroxidase substrate solution (KPL Inc.) was added to each well and absorbance of the developed color was measured by a colorimetric plate reader (Molecular Device)
The potential to exploit the induced expression of these enzymes as predictive markers and the opportunity this presents for drug design is discussed
Hemoglobin electrophoresis, red blood cell analysis, and hemolytic anemia screenings are required for black individuals with normocytic anemia
