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Similarly, although hepatic dysfunction can occur with large niacin doses (1-3 grams daily over months) causing elevated liver enzymes or jaundice, niacinamide at 100 mg is very unlikely to have any adverse effect on the liver
Additionally, the lower risk of blood vessel puncture and fewer nerve endings in the subcutaneous tissue in these areas make it a safe and effective option for peptide therapy [2]
The Pernicious Anaemia Society notes this is recognised but not fully understood
Real-world mechanism validation examples Glaucoma neuroprotection case: 65-year-old with moderate glaucoma, pressure well-controlled at 14mmHg on drops but showing 2-3% yearly visual field loss
References and Further Reading Pickart L
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