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Proper storage and handling are essential to preserve integrity

They slow gastric emptying, increase satiety, act on appetite signaling in the brain, and enhance glucose-dependent insulin secretion

Redox Biol (2018) 14:61825

This effect may help explain why positive findings appear across several different tissue types

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Immune balance is also influenced by broader systems involved in immune regulation and inflammation, including gut-associated lymphoid tissue (GALT) and the hypothalamic-pituitary-adrenal (HPA) axis, reinforcing the importance of addressing antioxidant capacity as part of a whole-system approach