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The protective effects of AC were also noted in the X-ray-radiated human skin fibroblasts

Given the abundance and diversity of ROS species present within biological systems, cells inevitably perceive and respond to distinct ROS species through specific mechanisms [101], thereby maintaining ROS homeostasis [16]

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Future Perspectives The scientific studies on seleno-GPxs have so far led to the understanding that the physiological role of seleno-GPxs is not only limited to detoxification of peroxides, but also involves regulating signaling pathways (such as chromatin remodulating, NF-B activation, insulin signaling, mitochondrial integrity, and ferroptosis, among others) [1, 8,9,10]

In studies of oxidative stress in epididymal epididymal cells in goats, miR-542-3p mRNA can downregulate the expression of GPX5, thereby aggravating oxidative damage in epididymal epididymal cells (Yang et al., 2022)