The pricing is genuinely competitive, especially the flat-rate model that does not penalize higher doses
This points to higher resting cardiovascular activation and reduced parasympathetic activity while on GLP-1s
"There are so many people on these medications, but they won't speak up about [the side effects]," says Reilly
These are dose-dependent and most prominent during the escalation phase, which is why both drugs are started at low doses and titrated gradually over several months
Plateau typically arrives between weeks 40 and 48
Recinella L, Orlando G, Ferrante C, Chiavaroli A, Brunetti L, Leone S (2020) Adipokines: new potential therapeutic target for obesity and metabolic, rheumatic, and Cardiovascular Diseases