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Assessment of thiamin (vitamin B1) and riboflavin (vitamin B2) status in an adult Mediterranean population

Together, these studies identified a histone acetylation pathway that is promoted by KG production and suggest demethylation reactions are dispensable for the observed HR-proficiency and corresponding resistance to DNA damaging agents

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Response rates in the clinical trial were not 100%, and some individuals simply do not show meaningful fat mobilization from this pathway

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