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Compared with conventional GLP-1 receptor agonists, such as liraglutide and semaglutide, tirzepatide has demonstrated superior efficacy in body weight control in several phase III clinical trials, with average weight reductions exceeding 20% in some study populations (15)

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A randomized pilot clinical trial of the safety of pioglitazone in treatment of patients with Alzheimer disease

Within this framework, glucagon-like peptide-1 (GLP-1) receptor agonists (RAs), originally developed for the treatment of type 2 diabetes (T2D), have recently shown cardioprotective effects beyond their role in glycaemic control

Following dosage recommendations did not show serious adverse side effects when taken for less than 12 months, but included stomach upset, breath and urine odour, and seizures in some cases

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