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Conversely, treatment with exenatide LAR was associated with improved FMD and carotid intima-media thickness, alongside metabolic benefits, in patients with type 2 diabetes (64)
International Journal of Sport Nutrition and Exercise Metabolism , 28 , 178-187
doi: 10.1038/nature00887 61 AbbottCRSmallCJKennedyARNearyNMSajediAGhateiMAet al
GLP- 1-based therapy exerts its pharmacological effects by activating the GLP- 1 receptor, a class of G protein-coupled receptor consisting of 463 amino acids
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Differential gene expression between hypervirulent and carrier strains affects numerous genes, many of which are involved in meningococcal metabolism, highlighting its importance in meningococcal disease, while other genes encode virulence determinants or proteins involved in genome stability and gene regulation ( Table 2 )
