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HE is primarily considered a gliopathy in which astrocyte dysfunction is the main neuropathological hallmark, while recently microglia and neuronal alterations have been reported
Abnormal insulin secretion in Parkinsons disease before and during L-dihydroxyphenylalanine (L-dopa) therapy
Naltrexone complements this process by blocking feedback signals that would normally limit that activity
However, there are a few things to consider
In this review, we discuss the mechanism of action of GLP-1 RAs, focusing on their proposed cardiometabolic impact and the key clinical trials that have demonstrated improvement in cardiovascular outcomes
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