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Sometimes there is a chemical so central to a process in human physiology that it would defy logic that supplementing the amount or function of the molecule should do anything other than make our health better

Renal hemodynamic effect of sodium-glucose cotransporter 2 inhibition in patients with type 1 diabetes mellitus

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Phentermine is not recommended for people with a history of heart disease, uncontrolled high blood pressure, hyperthyroidism, or glaucoma

Theres some scientific rationale supporting this possibility, as it has been hypothesized that GLP1 agonists may decrease rewarding/reinforcing effects of alcohol and other drugs of abuse