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The drugs efficacy and its role in mitigating the risk factors associated with cardiovascular diseases have cemented its position as a valuable tool in the therapeutic arsenal against diabetes and weight-related health issues
The catalytic serine S630 falls within the pentapeptide sequence Gly628-X-Ser630-Tyr631-Gly632, which is highly conserved across the / hydrolase protein family
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To address this gap, a novel UHPLC-HRMS method for the simultaneous detection and chiral resolution of three thiol enantiomers (DL-GSH, DL-Cys, DL-Hcy) in wine has been established, utilizing the chiral derivatization probe NCS-OTPP labeling
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