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The standard pharmacological rule of thumb is that after four half-lives about 94% has been eliminated and after five about 97%, which is why five half-lives is the conventional shorthand for "substantially cleared." Two caveats matter immediately
10.3390/antiox7100141 21 HerweckA
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Diagnostic methods Glutathione and sulphydryl compunds in erythrocytes can be measured using 5,5'-dithiobis (2-nitrobenzoic acid), while glutathione in fibroblasts can be measured with the 5,5'-dithiobis (2-nitrobenzoic acid) glutathione recycling assay [16], or using high performance liquid chromatography (HPLC) [17]
Cheleschi, S., Tenti, S., Bedogni, G
TLDR No validated human dose exists
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