tirzepatide injection site redness reaction : r/tirzepatidecompound Mounjaro Injection Site Reactions |

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GLP-1 drugs were initially developed for controlling blood sugar (glucose) levels in people with Type 2 diabetes

Genetic and biomarker factors also influence how quickly your body metabolizes semaglutide and how sensitive you are to dose gaps

Semaglutide was found to be inferior to tirzepatide, in a study of tirzepatide (LY3298176) vs semaglutide once weekly as add-on therapy to metformin in participants with type 2 diabetes (SURPASS-2), in both endpoints of reduction in A1C and body weight, with a roughly similar safety profile

Ali says both those drugs have been around for at least 12 years longer than Mounjaro, which was approved for diabetes management in 2022 (it is still not FDA-approved for obesity or weight management)

If fatigue is manageable at this level, there may be no need to increase further