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doi: 10.1016/j.phrs.2019.104554 12 TalenezhadNMohammadiMRamezani-JolfaieNMozaffari-KhosraviHSalehi-AbargoueiA
NAD(+) regulates Treg cell fate and promotes allograft survival via a systemic IL-10 [PMID: 26928119] Laboratory literature summary: NAD(+) regulates Treg cell fate and promotes allograft survival via a systemic IL-10 production that is CD4(+) CD25(+) Foxp3(+) T cells
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The microbiota transplanted from semaglutide-treated subjects to germ-free mice induced gut barrier dysfunction, systemic inflammation and an increase in the bacterial antigen load in the liver and adipose tissue, which activated the NF-B pathway to drive lipid accumulation
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