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Rates of serious adverse events were similar between the intervention group and placebo group (10% vs 8.1%)
Possible significance and implications for novel mediator
The drug, which stimulates GLP-1 and glucagon receptors, led to a 16.6% drop in body weight
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The GHinsulin-like growth factor 1 (IGF-1) axis and clock system may interact further on the metabolism through regulatory pathways in peripheral organs
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