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Other peptides worth comparing: Liraglutide daily GLP-1 agonist, less effective than both but FDA-approved since 2014 Retatrutide triple agonist (GLP-1/GIP/Glucagon), showing up to 24% weight loss in Phase 2 trials AOD-9604 HGH fragment for fat metabolism, much milder effect The Bottom Line Tirzepatide has the edge in raw efficacy and tolerability based on trial data

if you're still eating more than you burn, you won't lose weight

How fast do cardiovascular benefits appear This is the nuanced question

Two of the most common FDA-approved medications we prescribe are Wegovy and Zepbound

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The peptides discussed most are BPC-157 for pain and inflammation, Selank and Semax for anxiety and central pain processing, DSIP and the CJC-1295/ipamorelin pair for sleep and recovery, and thymosin alpha-1 and KPV for immune pathways