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Novo Nordisk and Eli Lilly now face discovery over allegations they ignored or concealed serious gastrointestinal risks while promoting these drugs aggressively for weight loss
Wurtman R
Contract manufacturers should establish a mechanism for evaluating MAHs and their products
Retatrutide may be better suited for those needing aggressive weight loss and deeper metabolic intervention
Additional contributing factors include: Prolonged gastric distension due to delayed emptying Changes in gastric motility patterns Individual anatomical variations, such as hiatus hernia Concurrent use of other medications that affect gastric function It is worth noting that obesity itself is a significant risk factor for GORD, as excess abdominal adiposity increases intra-abdominal pressure
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