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By targeting the repair mechanism along with a proper template for the correction of the mutation to the liver, the process can potentially restore the function of the liver cells to handle copper properly

This is the application area with the deepest preclinical history, and it is also where oral administration has a particularly direct anatomical rationale - the compound passes through the GI tract it was originally studied in relation to

BPC-157 increases actin synthesis at the gene level

doi: 10.1172/jci.insight.187072 97 LiuJLiKCaiJZhangMZhangXXiongXet al

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While it is effective, this additional step may reduce efficiency in some individuals