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The chemical reactivity of amino acid side chains is governed by nucleophilicity and basicity, both of which reflect the willingness of an atom to share its lone pair electrons
10.1016/j.dnarep.2005.03.002 DNA Repair 486 Vant ErveT
This is why these drugs are useful to treat diabetes
Most patients reach effective doses of 0.51.0 mg per week within 48 weeks, though some require higher maintenance doses
If side effects persist after several weeks, dose adjustment or medication change is recommended (21)
Although not yet fully understood, the likely cause is the ionizing UV radiation spectrum of sunlight
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