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The pharmacokinetic reasoning supports this (bypassing gut bacteria), but head-to-head comparisons of TMAO levels between routes have not been conducted in the context of compounded tirzepatide

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10.1016/s0014-2999(97)01033-9 121 SikiricP.SeiwerthS.MiseS.StaresinicM.BedekovicV.ZarkovicN.et al (2003)