Garca-Fernndez M, Castilla-Cortzar I, Daz-Snchez M, Dez Caballero F, Castilla A, Daz Casares A, Varela-Nieto I, Gonzlez-Barn S
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Behav Brain Res (2017) 326:23743
The study design tells us exactly what the researchers considered safe and effective starting points
The completed study demonstrated significant efficacy with 45% clinical response in the AJM300 group versus 21% in placebo (OR 3.30, 95% CI 1.73-6.29, p=0.00028), good tolerability with similar adverse event rates between groups, and established AJM300 as a potential novel induction therapy for moderately active UC
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