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The emergence of a metabolic drug that incidentally reduces addictive behavior underscores something many clinicians have long suspected: addiction is deeply intertwined with the bodys fundamental regulatory systems appetite, satiety, stress, reward, inflammation including behaviors like binge eating that share overlapping neural pathways

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Since then, multiple GLP-1 drugs approved for obesity and diabetes treatment have hit the market, with more in development

Both groups improved significantly by 20% compared with baseline at d 28 (mean decreases of ARA 290 = 3.9 1.9 and placebo = 3.7 1.5

publicly available FDA regulatory communications

R., Fritsche, A., Gribble, F