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Dhillon, S., & Keam, S

While clinical trials show patients losing between 15% and 22% of their body weight on these medications, the most meaningful results are often the "non-scale victories," like having the stamina to play with your children or feeling comfortable in your favorite clothes again

Clinical trials have shown that side effects, including fatigue, are most prominent during the first few weeks of therapy and often diminish as the body adapts to the drug

Deacon, C

Many patients start seeing changes within the first 4 to 6 weeks based on dosage and consistency

And the enhanced AO activity has been linked with decreased stress tolerance (Garchery et al., Interestingly, the function of this enzyme in the past was often confused or neglected in several studies, so it requires to be elucidated well