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Before starting any GLP-1, patients need baseline assessment for thyroid history, pancreatitis risk, kidney function, and medication interactions
USE IN PATIENTS WITH RENAL IMPAIRMENT Two trials are available examining the impact of renal impairment on oral semaglutide safety, tolerability, and pharmacokinetics
doi:10.1097/ms9.0000000000003370 Huang Y, Wei Y, Liang F, et al
Both trials used gold-standard randomized, double-blind, placebo-controlled designs
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