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Its sequence is Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu

Hypercalcemia can be very discomforting as it causes stomach upset, vomiting, weakness, and frequent urination

However, the largest Phase IIb trial involving 536 participants failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading to development termination in 2007

Inhibitors of glutathione S -transferases as therapeutic agents

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In addition to activating the GLP-1 receptor, it also stimulates the GIP receptor, which plays a role in fat metabolism and energy balance