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Severity of Deficiency : Severe deficiencies often require injections to restore B-12 levels quickly
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Patients with vitamin B12 deficiency and concurrent renal or hepatic disease may require increased doses or more frequent administration of cyanocobalamin
According to primary care experts, intramuscular shots help quickly restore blood levels of B12 in the body
Low potassium levels, which can lead to constipation, an irregular heartbeat, leg cramps, numbness or tingling
Metformin may result in suboptimal oral vitamin B12 absorption by competitively blocking the calcium-dependent binding of the intrinsic factor-vitamin B12 complex to its receptor
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