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After at least two years of treatment, GLP-1 users had a 37 percent higher chance of developing alopecia than patients taking SGLT-2 drugs and 68 percent higher odds than those taking DPP-4 drugs, both of which are also used to treat type 2 diabetes
Tirzepatide showed higher average weight loss in SURMOUNT trials, while semaglutide has a very large GLP-1 evidence base
Some people lose less weight on semaglutide or tirzepatide than expected
The reality is that BPC-157 exists in a gray area
Going up in dose too fast is a frequent reason people feel worse than necessary
moderate renal impairment (eGFR 30-45 ml/min) has been observed to increase plasma levels of sitagliptin 2-fold, and severe renal impairment can increase plasma levels 4-fold
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