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NAD+ therapy aids mitochondrial health, energy, cognition, and inflammation.[20][33][39] IV forms provide rapid boosts, with studies showing safety and efficacy in fatigue reduction

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It does not make eating less feel easier, does not reduce cravings, and does not change food preferences

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NNMT is expressed in some cancer cells, which makes interpretation of inhibition complex: effects could differ by cancer type or stage, and the data are largely from models rather than long-term human study