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Adverse Events Reported with Compounded Semaglutide and Tirzepatide The FDA has received reports of adverse events tied to compounded versions of both semaglutide and tirzepatide

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After 24 weeks, mean weight loss with phentermine/topiramate ER in PCOS obese women was 8%, even higher than the 6.6% Weight loss reported at 56 weeks in the general population [171] However, cardiovascular safety concerns persist for this drug, particularly in people with PCOS, who are already at increased risk for cardiovascular complications compared to the general population [172]

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