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The pooled estimates may be underestimates of the efficacy of newer agents, although the review could not determine whether stronger weight-loss effects necessarily translate into greater reductions in binge eating

Functional medicine emphasizes treating the whole person by considering their unique physical, mental, and emotional needs, integrating various scientific tools to address individual health complexities

doi: 10.1038/s41541-021-00391-8 242 SasaiM.YamamotoM

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The relevance of metabolic modulation for treatment response is further supported by evidence showing that metabolic status significantly influences the effectiveness of systemic therapies in PsO