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Despite these promising developments, the clinical translation of nanoparticle-based strategies faces challenges including concerns regarding their stability in vivo and the need for further research to validate their safety and efficacy

PDE4, despite its relevance to cortical cAMP signaling, is hindered by intolerable side effects such as nausea and vomiting, which have repeatedly limited clinical progression (Sharma and Purohit, 2023)

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In contrast, CGRP treatment had no effect on expression of other HSV-1/2 entry receptors (Supplementary Fig

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[DOI] [PubMed] [PMC] Adelusi OB, Ramachandran A, Lemasters JJ, Jaeschke H