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These modications extended the half-life to approximately 13 hours, allowing for once- daily subcutaneous injection
The NNTs for SGLT-2 inhibitors to reduce mortality are truly impressive, although 1 in 7 patients will get an additional genital infection in five years
Semaglutide targets only the GLP-1 receptor and achieved 14.9% mean weight loss at 68 weeks in the STEP 1 trial
A major study, published in 2025, on the link between the intake of various food groups and risk of overweight and obesity found diets rich in whole grains, legumes, nuts, and fruit are linked with a lower risk of overweight and obesity (8)
These advantages are encouraging healthcare providers and patients to adopt innovative oral GLP-1 receptor agonists for the management of metabolic disorders
Patients with obesity have yet another option in their arsenal to fight access weight that is not only very effective but also seems relatively safe, at least in the short and medium term
