Following this spike, switching rates declined after the spike but stayed elevated (~1.6%) through September before returning to baseline in October 2025
Great ways to bring TPO numbers down are by eating an anti-inflammatory diet 18 19 20 21 22reducing sugar, processed foods, trans fats, gluten, and alcoholand adding in selenium 23 24 and vitamin D supplements 25 26
A recent phase Ib study of tarlatamab, a bispecific T-cell engager targeting DLL3 and CD3, in 40 NEPC patients demonstrated a manageable safety profile with promising antitumor activity, including partial responses in 22.2% of DLL3 + NEPC patients 158
Your prescriber will plan a clean transition
Both have similar side effects (like nausea) that improve over time
[16] Sharma A, Tiwari M, Gupta A, Pandey AN, Yadav PK, Chaube SK