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A clinical trial by Meissner and colleagues with the GLP-1 lixisenatide demonstrated a modest reduction in motor disability progression in patients with early-stage PD
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Lacking significant correlations between purine metabolites (UA and Xan) and 5-HIAA suggest that alterations in key serotonin pathways may both be modified by and contribute to oxidative stress via purine catabolism in FENNS
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