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DPP-4 inhibitors, such as sitagliptin, alogliptin, linagliptin and saxagliptin, were synthesized to prolong the half-life of GLP-1 (102)

In accordance with the classical model of food intake control GLP-1 action on feeding has been primarily ascribed to receptor populations in the hypothalamus and the hindbrain

This exam should include dilated fundoscopy, optic nerve assessment, and documentation of any pre-existing diabetic retinopathy or risk factors for NAION

Patients are advised to: Maintain adequate hydration by drinking plenty of water throughout the day, which helps the kidneys excrete uric acid more effectively Limit intake of purine-rich foods such as red meat, organ meats, certain seafood (anchovies, sardines, mussels), and high-fructose corn syrup Moderate alcohol consumption , particularly beer and spirits, as alcohol can increase uric acid production and reduce its excretion Achieve and maintain a healthy weight through balanced nutrition and regular physical activity, as obesity is strongly associated with hyperuricaemia Avoid rapid weight loss , which can paradoxically trigger acute gout attacks by temporarily raising uric acid levels Monitoring is important for patients with known hyperuricaemia or gout

Next Step: If you havent started your journey yet, take our free assessment quiz to see which personalized GLP-1 program is right for your health goals

Adjustment Usually Happens Gradually The body may need several weeks to adjust