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Novo Nordisk revealed positive Phase 3 data from the PIONEER TEENS trial showing that oral semaglutide significantly reduced blood sugar in children and adolescents aged 1017 with type 2 diabetes, with a safety profile consistent with prior semaglutide studies
An early FAERS analysis suggested an elevated risk, prompting the FDA to investigate
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The general consensus is that any increased risk of retinopathy with GLP-1 RA treatment is likely to be related to the abrupt improvement in glycemic control [108], a phenomenon similar to that reported for other neuropathological complications [109]
doi: 10.1007/s10930-015-9629-7 66 KaganV.MaoG.QuF.AngeliJ.DollS.St CroixC.et al
GSH also plays an important role in energy metabolism
