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Abstract Many local and systemic diseases especially diseases that are leading causes of death globally like chronic obstructive pulmonary disease, atherosclerosis with ischemic heart disease and stroke, cancer and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease 19 (COVID-19), involve both, (1) oxidative stress with excessive production of reactive oxygen species (ROS) that lower glutathione (GSH) levels, and (2) inflammation
If the balance is not maintained it leads to loss of hard-earned muscle and impaired muscle protein synthesis
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doi: 10.1182/blood.2019003990 81 HoJLZhuBHeSDuBRothmanR
J Strength.Cond.Res
Type 2 diabetes substantially increases the risk of cardiovascular events, and glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have been shown to reduce major adverse cardiovascular outcomes
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