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Interestingly, scurvy, which is an extreme vitamin C deficiency, is associated with a breakdown of gut barrier function
If the deficiency was purely dietary, oral supplementation may be considered after initial repletion
Diagnosing SIRVA can be challenging, as shoulder pain is a common symptom shared by a variety of medical conditions
For people with an MTHFR mutation, methylcobalamin (as opposed to other forms of B12) is therapeutic
(PubMed) Wu X, Yang K, Tang X, et al
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