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C., Kauppinen, R., Rhodes, L
The studys findings are also supported by the observed safety profile, where most adverse events (AEs) being mild to moderate gastrointestinal issues, consistent with the known effects of oral semaglutide
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The pivotal SURMOUNT-1 trial that established tirzepatide's weight-loss efficacy capped doses at 5, 10, and 15 mg weekly and showed 20.9% mean body-weight reduction at 15 mg over 72 weeks (Jastreboff et al., 2022)
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