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The Use of Testicular Sperm for Intracytoplasmic Sperm Injection in Patients with High Sperm DNA Damage: A Systematic Review
We acknowledge that the intervention is complex, likely to require at least 10 years of intervention for the endpoint of cancer incidence, and would include behavioural strategies to supplement the chemoprevention during weight loss intervention and maintenance
It is essential to distinguish between theoretical concerns, preliminary signals in preclinical research, and actual evidence of increased cancer risk in humans
Elevated cortisol promotes visceral fat storage, increases water retention, impairs muscle recovery, and can trigger emotional eating patterns that the medication only partially counteracts