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The specific sites of action and underlying molecular mechanisms that mediate GLP-1R-induced body weight loss are currently being investigated

The principles are identical

We report that L-GSH supplementation for 3 months in people with T2DM was able to reduce the levels of oxidative stress in all blood components and prevent depletion of glutathione (GSH) in this population known to be GSH deficient

10.1016/j.pmpp.2017.07.006 2 Agudelo-RomeroP.ErbanA.RegoC.Carbonell-BejeranoP.NascimentoT.SousaL.et al

Mantovani, G., Maccio, A., Madeddu, C., Gramignano, G., Serpe, R., Massa, E., Dessi, M., Tanca, F

Oestrogen dependence may be due to the upregulation of the 17-hydroxysteroid dehydrogenase-1 and aromatase genes, whereas progesterone resistance may result from the failure of progesterone receptor activation and transcription of progesterone target genes [99]