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Most patients who complete a full 12-week protocol and maintain adequate protein intake and training consistency report 2 to 4 pounds of lean mass gained and a 1 to 3 percent reduction in body fat percentage
This reflects both the higher dose used for obesity (2.4 mg vs typical diabetes doses) and the superior pharmacological properties of the molecule
However, consuming fewer calories today does not immediately translate into visible fat loss tomorrow
GLP-1 medications have changed the game for weight loss, but not everyone sees the same results
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Both medications are effective, but tirzepatide's greater average effect size has made it the faster-growing segment of the GLP-1 market
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