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Still, we can speculate what might be happening based on our understanding of how the body responds to weight loss, including altered metabolism, reduced blood flow to extremities, decreased food-induced heat production, and loss of insulating body fat
However, its always best to consult a healthcare provider before starting any new supplements, as they may be unnecessary or could interact with other medications
August 4, 2023
One possible explanation for the similar effects on weight loss observed with both GIPR agonism and antagonism might be that chronic pharmacological GIPR activation induces functional antagonism in a subset of neurons through receptor desensitization, as seen in adipocytes, isolated pancreatic islets and mouse neuroblastoma Neuro2a cells 36,37
Glutathione can be taken with or without food, though some users prefer taking it in the evening to support overnight detoxification processes
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