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While blood clots are not a recognized side effect of GLP-1 medications, patients should remain aware of warning signs, particularly given that obesity itself increases thrombotic risk
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Approximately 75% of patients were also taking metformin
There is evidence from animal studies that glucagon activation stimulates thermogenesis through brown adipose tissue, essentially turning stored fat into heat
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Cultures were maintained in a humidified atmosphere of 5% CO 2 at 37C for 24 h and then incubated for the next 24-h period in DMEM-10% HS additionally containing recombinant HGF that was treated with peroxynitrite with or without trisulfide pre-treatment (see Figure 1d,f)
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