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This accumulation is mediated by plasmalemmal transporters predominantly expressed in glial cell, such as divalent metal transporter 1 DMT1/SLC11A2 or zinc transporter ZIP14/SLC39A14, 374,375 which both transport Fe 2+ (ferrous), whereas Fe 3+ (ferric) is accumulated through transferrin receptors
This process has been demonstrated to involve the association with oligomerized PRDX2 17
Int J Vitam Nutr Res Suppl
10 There is no standardized treatment duration, but most studies utilized twice a day dosing for 12 to 24 weeks duration
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AA metabolites were remarkably elevated in psoriatic lesions compared to healthy individuals and non-lesioned skin samples
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