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the toxic effects of SSRIs on the mechanism of toxic effects of SSRIs on the reproductive system has not been fully clarified, and although some studies have explored mechanisms such as oxidative stress, changes in hormone levels, and apoptosis, they lack systematic and in-depth nature, and lack in vivo model validation
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Peptides can influence hormone levels, metabolism, appetite, blood sugar regulation, and other physiological systems
Research interest nonetheless expanded considerably through the 1980s and 1990s, as investigators began exploring DSIP's broader neuroendocrine roles, including its interactions with the HPA axis, circadian timing systems, and stress-response pathways, establishing the compound as a multifunctional regulatory neuropeptide whose biological significance extends well beyond its original sleep-focused characterization
Consultation with a clinician is essential in such cases
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