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Subjective and physiological effects, and expired carbon monoxide concentrations in frequent and occasional cannabis smokers following smoked, vaporized, and oral cannabis administration
Deliverables Each metabolic stability project delivers a comprehensive data package designed for direct use in compound progression decisions and regulatory documentation: Method Development Report LC-MS/MS method parameters, LLOQ, linearity, and system suitability data Raw Data Tables Peak area ratios, % remaining at each time point, replicate data Depletion Curves Semi-log plots of % remaining versus time for each test system and species Calculated Parameters In vitro t, CL int (L/min/mg or L/min/10 6 cells), scaled CL hep (mL/min/kg) QC Documentation System suitability results, QC sample accuracy and precision, batch acceptance summary Species Comparison Summary Side-by-side comparison of metabolic stability parameters across all species tested Demo Results The following representative data illustrates the type of metabolic stability results generated using our platform
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Ann Rheum Dis (2016) 75(2):4308
Imbayagwo, L
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